Precision Cardiovascular Medicine & Population Genomics
Our mission is to transform cardiovascular care through genomic discovery and precision medicine implementation.
We harness the power of large-scale biobank data and advanced genomic analyses to uncover the genetic basis of cardiovascular diseases. Our work spans from initial discovery to clinical implementation, with a particular focus on atherosclerotic diseases, aortic conditions, and heart failure.
Through collaboration with the Million Veteran Program, Penn Medicine Biobank, and other major cohorts, we're identifying novel genetic variants that affect disease susceptiblity, which we use to develop new therapeutic targets and personalized prevention and treatment strategies that account for each individual's genetic risk profile.
70+ peer-reviewed publications
10+ trainees mentored
3 active grant-funded projects
IL-6 pathway advanced to clinical trials for PAD
Leading multi-center genomic studies
Novel therapeutic targets identified in AAA
